Label-free biosensing with functionalized nanopipette probes
نویسندگان
چکیده
منابع مشابه
Label-free biosensing with functionalized nanopipette probes.
Nanopipette technology can uniquely identify biomolecules such as proteins based on differences in size, shape, and electrical charge. These differences are determined by the detection of changes in ionic current as the proteins interact with the nanopipette tip coated with probe molecules. Here we show that electrostatic, biotin-streptavidin, and antibody-antigen interactions on the nanopipett...
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Nanopipette technology has been proven to be a labelfree biosensor capable of identifying DNA and proteins. The nanopipette can include specific recognition elements for analyte discrimination based on size, shape and charge density. The electrical read-out and the low cost fabrication are unique features that give this technology an enormous potential. Unlike other biosensing platforms, nanopi...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2009
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0900306106